Understanding Non-Stimulant Laxatives: How Do They Work? (2024)

Non-stimulant laxatives, also known as osmotic laxatives, are a type of laxative that helps treat constipation by softening hard stools. They work by pulling water from other body parts and sending it to the colon, which softens the stool and makes it easier to pass. They are generally considered the gentlest type of laxative and are often recommended as the first course of treatment for constipation. Examples of non-stimulant laxatives include polyethylene glycol, magnesium hydroxide solution, and glycerin.

Non-stimulant laxatives are also called osmotic laxatives

Osmotic laxatives include milk of magnesia and glycerin. They are available over the counter and are generally considered the gentlest laxatives. They are the least likely to cause side effects and are often the best laxative to try first.

Other types of laxatives include:

• Bulk-forming laxatives: These laxatives add soluble fiber to the stool, making it bigger and softer. The size increase stimulates the colon to contract and push out the stool.
• Stool softeners: These increase the amount of water and fat absorbed by the stool, softening it.
• Lubricant laxatives: These coat the colon, making it slick and preventing the colon from absorbing water from the stool.
• Stimulant laxatives: These activate the nerves that control the muscles in the colon, forcing the colon to move the stool along.

They work by retaining water in the colon

Non-stimulant laxatives are a type of laxative that can be taken to relieve constipation. They work by drawing water into the colon, softening stools, and making them easier to pass. This is in contrast to stimulant laxatives, which work by stimulating the lining of the intestine and accelerating the stool's journey through the colon.

Non-stimulant laxatives include osmotic laxatives, such as polyethylene glycol (found in brands like Miralax), and saline osmotics, such as magnesium-based laxatives like milk of magnesia or magnesium citrate. These laxatives work by drawing water into the bowels, increasing the water content and bulk of the stool, and triggering bowel movements. This makes the stool softer and easier to pass.

It is important to drink plenty of fluids when taking non-stimulant laxatives to ensure they are effective and to reduce the possibility of side effects such as gas and cramps. While non-stimulant laxatives are generally well tolerated and safe, they should still be used sparingly and only as directed by a doctor. Prolonged use of laxatives can lead to laxative dependency and may interfere with the absorption of certain vitamins and medications.

In summary, non-stimulant laxatives are an effective and gentle option for relieving constipation. They work by retaining water in the colon, softening the stool, and facilitating bowel movements. When used appropriately and under medical guidance, they can provide relief without the same dependency risks as stimulant laxatives.

They are available as liquids, caplets, enemas or suppositories

Non-stimulant laxatives are available in a variety of forms, including liquids, caplets, enemas, and suppositories. Each form has its own advantages and disadvantages, and the choice depends on individual preferences and needs.

Liquids

Laxatives in liquid form are easy to consume and may be measured out and drunk directly. They are often available over the counter and can provide quick relief from constipation. However, it is important to follow the instructions on the label to prevent side effects and ensure effectiveness.

Caplets

Caplets, or capsule-shaped tablets, are another convenient option for taking laxatives. They are typically taken by mouth and may be preferred by those who find it difficult to swallow pills or liquids. Caplets are also available over the counter and provide a discreet way to take laxatives.

Enemas

Enemas are small squeezable tubes that are injected into the anus to deliver the laxative directly to the affected area. They are known for providing fast relief, usually within 15 minutes to an hour. However, they also carry a higher risk of side effects such as diarrhea and stomach cramps. Enemas are generally not recommended for long-term use.

Suppositories

Suppositories are tiny dissolvable capsules that are inserted into the anus and are also known for providing quick relief. They stimulate contractions and are usually administered rectally. Like enemas, suppositories are not recommended for long-term use and carry a risk of rectal irritation and discomfort.

They are generally considered the gentlest laxatives

Bulk-forming laxatives are generally considered the gentlest type of laxative. They are also known as fibre supplements and are available over the counter. They work by drawing water into the stool, making it softer and easier to pass. They are safe to use daily and include psyllium (Metamucil®), polycarbophil (FiberCon®) and methylcellulose (Citrucel®).

These laxatives are least likely to cause side effects and are often the best option to try first. However, they can take a while to take effect, from half a day to several days. They are also the type most likely to cause flatulence and bloating.

Other types of laxatives include:

• Osmotic laxatives, which pull water from other body parts and send it to the colon. They include polyethylene glycol (MiraLAX®) and magnesium hydroxide solution (Milk of Magnesia).
• Stool softeners, which are also called emollient laxatives. They include docusate (Colace®).
• Lubricant laxatives, which coat the colon and include mineral oil.
• Stimulant laxatives, which force the colon into motion and include bisacodyl (Dulcolax®) and senna (Fletcher's® Laxative).

They include milk of magnesia and glycerin

Non-stimulant laxatives are osmotic laxatives that treat constipation by drawing water into the intestines, which helps to induce bowel movements. They are also used to treat symptoms caused by too much stomach acid, such as heartburn, upset stomach, or indigestion.

Milk of Magnesia is a non-stimulant laxative that contains magnesium hydroxide. It is used to treat occasional constipation and reduce stomach acid. It is available in a chewable form and a liquid form. The dosage is based on the user's medical condition and response to treatment. It is important to note that extended use or overuse of Milk of Magnesia may result in dependence on laxatives and ongoing constipation. It may also cause dehydration and mineral imbalances if overused.

Glycerin is another non-stimulant laxative that belongs to the drug class of laxatives. It is used to treat constipation and there are no known interactions between glycerin and Milk of Magnesia.

Both Milk of Magnesia and glycerin are effective non-stimulant laxatives that can provide relief from constipation without the side effects associated with stimulant laxatives.

Frequently asked questions